Hi, I've had a bit of a journey with HRT and wanting some advice. I've been on HRT about 10 years and I'm 57. I was on Femoston 2/10 until the meno clinic wanted me to change to patches, ended up with a mirena but I had hair loss so they took it out. I also had my patch dosage increased and I'm now on Estradot 75 and Utrogestan since late October. This regime seems to suit me so far, except I have morning nausea and sore boobs (one very sore!). Does anyone know whether 75mcg is very high and does it massively increase my breast cancer risk? I know there was a study that found continued breast soreness (after a few months?) increased the cancer risk. They have discharged me from the meno clinic and my GP has no clue about HRT. I had an estradiol blood test and it was 151 p/mol. I'm wondering if I should reduce to a 50mcg patch again?