Hi Flan747
What oestrogen dose are you on and do you know if you are post-menopausal or not?
The recommendation for utrogestan is that it should be taken on an empty stomach or something like 2 hours after a meal so most women take it at bedtime I think. The reason is that bioabsorption is increased when taken with food, and maybe more the point that if you took it after variable amounts of food you might not get a consistent dose which could lead to variation in prog levels and therefore breakthrough bleeding.
Many women take it vaginally because more of the prog goes directly to the uterus to work on and protect the lining. However if you are taking it continuously you probably wouldn't want to do this?
Hope this helps and good luck with your new regime
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Hurdity x