Hello, I am new to the forum and need help. I am in perimenopause and was experiencing night sweats, muscle and joint pain, and VA. I started using compounded Estradiol cream and brought my levels up to 69.7pg/ml. My progesterone is 0.19ng/ml. I still have some minor VA symptoms, but all other issues are completely gone. The only problem is I can not get on progesterone (i have uterus). I have tried oral and sublingual Micronized Progesterone, starting with the very low dose of 25mg. Even at that low dose I get adrenal rashes (like I had too much coffee) and feel like somebody poisoned me; then after about 10 hours I become sedated, start cramping and peeing all the time. On top of that I have got IBS flare up oral progesterone. I have also tried progesterone cream and started with a little bit, something around 6mg of progesterone on my skin. The cream did not give me the adrenalin rush, but also gave me sedation, cramps, and peeing. I do not know what to do as I do not want to give up estrogen as it helps with all my health issues. I would really appreciate your advise.