Yes, it used to say discard the first 3 pumps which is loads of gel. I don't. I discard a little pump, maybe as big as a peanut, then use it. If it's less effective for a day it's no great shakes.
I think I've mentioned before that I write the date I start it on the top of the cap so I know when it's due to run out in case I go on holiday etc (like that's going to happen in the next 18 months!!!). That helps too. But it's amazing how much you can get out of one of those suckers! X