Hi Sammie Jane .. Coincidently I have just started taking these - I'm just going into my third week. (I was the one who posted separately about slurred speech which is an ongoing pre-HRT issue) but yesterday I was also suddenly hit by a really dihabilitating lower back pain. Luckily I don't work Wed/Thu as I am literally shuffling around the house. I think its got to be a side effect as I never get back issues. I was prescribed 1/2 mg with the advice to take one or two tablets per day as needed. I was taking two a day as my brain fog/headaches were quite severe. I now think this is too much and I probably need to go a bit easier on one a day but I will need to further clarify this with the GP. At least the headaches have lifted but if its not one thing, its another! Apart from that maybe the odd mild stomach ache but nothing major.