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hi anaisei have used ovestin for a year now but i swapped from vagifem to this but i would do a loading dose first it tells u in the leaflet i think it's same as vagifem every night for two weeks then twice a week x i'm not sure the estrogel was causing my hairloss u know as first week stopped shedding and this second week it's been shedding again same amount as on the estrogen x so don't know what i'm going to do x hope ur ok 👌 other then the Va