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Author Topic: Progesterone intolerant  (Read 1147 times)

trumpera

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Progesterone intolerant
« on: August 05, 2019, 06:47:39 PM »

Hi,I've been in oestrogen for 2 months but am progesterone intolerant. Progesterone results in debilitating anxiety,utrogestin milder anxiety but my bowel stopped moving for 48 hours . I had endometrial resection 15years ago with no bleeding since but still need progesterone.  I'm applying 1/half pumps with great effect.  I fear i may have to stop or consider hysterectomy of i don't find something I can take. Ive been seen by a gynae  proof  who  advised progesterone 5mg next to try. Has any had similar experience ? 
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trumpera

  • Guest
Re: Progesterone intolerant
« Reply #1 on: August 05, 2019, 06:51:53 PM »

I meant dydrogesterone ...spell checker 😜
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MicheleMaBelle

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  • Posts: 602
Re: Progesterone intolerant
« Reply #2 on: August 07, 2019, 08:09:22 AM »

I think it can be kinder than some progesterones but as this is the part of HRT that a lot of us struggle with, it's difficult to know what might work for you.
Are you on a cycle, do you take it for the whole month or part of it?
Some women seem to get on well with Provera, but I don't have any experience of this. I take Utrogestan on a slightly reduced basis ( 10 days instead of 12 ) . I still have side effects but I've just decided to put up with them as I don't want to stop HRT right now.
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Perinowpost

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  • Posts: 1005
Re: Progesterone intolerant
« Reply #3 on: August 07, 2019, 08:33:40 AM »

Hi Namaste

It's a really common problem and one many of us struggle with while trying to find a balance. I have just trialled 2 months on dydrogesterone (Femoston 1/10) as I was struggling with utrogestan.I would say there were some positives and some negatives.

The positives were the dydrogesterone didn't affect my mood as much as the utrogestan, or quash my libido at all actually.

The negatives were I felt drugged up (sedated) the whole time I was on it.  As I have to take it longer than utrogestan 12 days as opposed to 7, and then factor in the withdrawals I'm not sure it was worth it. The jury's still out on that one (currently withdrawing from month 2).

The problem is (I was advised by my specialist) my receptors are particularly sensitive. I suspect all of us having these issues are in the same boat. It's about time we had more options, this is something that's been said many times before but there's no sign of any progress yet! That said dydrogesterone may work for you, it's worth a try. Sorry I can't be of more help x
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trumpera

  • Guest
Re: Progesterone intolerant
« Reply #4 on: September 02, 2019, 08:33:38 PM »

I think I'm going to continue estrogel only, very low dose for a few months then try to wean off. I can't even tolerate tibolone. I recognise estrogen runs a risk if unopposed. I know a successful endometrial resection could leave some microscopic endometrium behind, but I can't continue with the debilitating impact on my quality of life.
Perhaps I'll try a low dose antidepressant.
 :-\
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