I'm hoping someone can advise please..my Mother (91 years) has had problems with her vagina for years, we have tried everything, she takes Lyrica for the pain every day, morphine patches a few years ago and even beta blocker injections, she says nothing has eased the pain and some days it's better than others... so fast forward, she is now in a Care home and I have spoken to her new GP, who was lovely and supportive, I told her about Mum's history I and suggested it could be post menopausal atrophy, the GP agreed and she has prescribed Mum an HRT cream to try first which has been administered by the District Nurse a couple of days ago. I called my Mum today to see how she was getting on with the cream and she said that it has made the pain worse.. is this possible?