Well, I'm only 2 and a half weeks in. And I started on half patches. So it's a bit early.
But, I started on half patches because I was worried I would have a skin reaction. I'm very happy to say I've had no reaction. They stick well. The old one stays on well through a bath. If one did come off there would be no sticking it back on. When the old one comes off, it's taking a layer of my dry skin with it (no worries about that), but means it loses its' stickiness.
I could definitely tell I was absorbing the estrogen in the first couple of weeks. I felt a tingling in my skin. Not where the patch was, but in my legs. More than pins and needles, but not terribly painful. Just uncomfortable and noticeable. That's gone now.
Some ladies report improvement in things like hot flushes in the first month, and improvement in mood and anxiety after 3 months. My biggest issue is anxiety, so I'm being patient.
Boombod - get them stuck on, and then relax, be patient and try not to obsess.
Easier said than done ... I know