I'm 45, started peri 7-8 years ago. Tried synthetic HRT 2 years ago - made me depressed zombie, and I stopped within a month. A year later, I saw a new doc. On bioidentical hormones now: 0.625 estradiol, and 200 mg utrogestan daily. The physical issues are much improved, but the mental side of peri is destroying my marriage, and causing me terrible anxiety/depression.i recently had an ultrasound due to 4 periods in 6 weeks, then I only went 9 days before bleeding again. Uterus looked fine (3.5mm lining) and one ovary had a 3x3x3cm cyst. Next step was endometrial biopsy which was normal, thank goodness. I'm thankful that nothing bad was found, but I have NO IDEA how to keep going like this. I've tried several antidepressants without success. I weight-lift 5 days a week, walk 2 miles a day, try to do yoga a few times a week, etc, but the mood swings, irritability, and depression are overwhelming. My husband of 27 years tries to be understanding, but who can tolerate the swings daily for almost a decade?
So, my question: if I get a total hysterectomy and BSO, will that allow me to find a stable HRT regimen that will eliminate these crazy swings? I know the meds will need to be adjusted without my evil ovaries kicking in some hormones and that will take some time, but at least the levels will eventually be stable? Is this unrealistic optimism? I don't take the seriousness of the surgery lightly, but my marriage and life are both at critical point.
Thank you all. This forum and the menopause subreddit have been such a blessing through this time. I can't thank you ladies enough!