I know what you mean about your brain permanently connected to your bladder. I thought it might be psychosomatic but then I have a few normal wee days and I know I'm not. I feel awful today. I have been like this for 6 months after a bout of cystitis. I'm desperate to feel ok. Katejo, how long have you been on vagifem and are you on other hrt. I think I may have asked you that before. I daren't even have sex I'm so frightened about cystitis. We just have to try and stay positive Mrs Bennet, but it all seems so bloody unfair.