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Author Topic: Anybody had Hysterectomy due to severe progesterone intolerance (HRT)?  (Read 4407 times)

Night_Owl

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Thanks for comments.

Paisley, appreciate your honesty - sorry to read that you're still struggling, sounds lame but hope you find some stability in time. 

So true every woman is different and unfortunately I'm *always* in the minority, hyper-responsive category who doesn't respond well to medication/treatment, just to add insult to injury, so sick of my weak constitution.  Over the years I've discussed hyster with the Meno Clinic and pondered for so long as of course it's such a massive decision - through fear I already imagine changing my mind and jumping off the operating table at the last minute just before anaesthetic!  My ovaries are now "undetectable" on scans so they would be left in place.

Duavive I don't see as an option for ethical reasons and prefer transdermal.

If I come off HRT altogether, without estrogen I will be back to feeling (more) suicidal with constant migraine and worsened anxiety/depression, a life not worth living.  However a life with taking progesterone, albeit every 6 weeks, is still life-ruining, of no quality with the psychosis/imbalance/disruption it causes.  We are all so hugely different, some women are fine  on it.

If only there were more choices of HRT for progesterone intolerance.

Tried various ADs in the past, all gave hideous side effects.

No solution really ... sigh ... round and round in ever decreasing circles, no hope.

The sun is shining but couldn't feel more miserable.  Sorry for the whinge, very low in spirits. 
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Mary G

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Night_Owl, I'm sorry you are feeling so low but it's understandable.

Honesty, I think you have reached the end of the road and a hysterectomy is your best option.   You clearly can't tolerate progesterone at all and like me, you desperately need oestrogen to feel good and keep the migraines away - there is a link between migraines and depression incidentally.

The fact that your ovaries are no longer viable should mean you don't have the side effects that younger women have when they have a full hysterectomy. 

Think of the benefits, no progesterone ever again, no periods, no more uterine scans or at least not the endless scans that progesterone intolerant women have to have.

I know it's difficult but you might feel better when you have spoken to a specialist about the operation.
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paisley

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Hi Night-owl
I certainly don't want to put you off as the big advantage is not to have progesterone anymore. I do class that as a really big plus. I just thought that after I had had a hysterectomy it would be a doddle for me to only have to think about Oestrogen & stabilizing on that would be so easy but it wasn't. I have read on other sites about women who have had hysterectomies & sailed through it & feel fantastic. I unfortunately just seem sensitive to hormones with progesterone being the absolute worse. So have a good look around on other sites where women have had hysterectomies & see how they are doing & coping. I hope you too can find stability. Xx
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walkingthedog

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Night owl
Sorry for late reply I have had problems getting on forum
I couldn't tolerate any progesterone and my womb lining was getting thicker no matter how much they gave me. I eventually agreed to the mirena coil out of sheer desperation and it didn't help my womb lining. Due to this the consultant said I could have a hysterectomy which i was over joyed with due to the increasingly growing womb lining and the progesterone intolerance plus pms! My hysterectomy was March 2017 and I can honestly say it's the best decision I made. I haven't looked back.
I use sandrena gel for the estrogen, it was a straight forward operation done via laparotomy
I know I very lucky and not everyone has such a good outcome but it was the correct decision for me
Xx
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Tempest

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I had to reply to this, Nightowl. Please, please don't have your ovaries removed unless you absolutely have to. Hysterectomy - ok. Oophorectomy - complete other ball game. Trust Paisley and I - this is a very, very tough road and getting HRT right isn't as easy as many people assume who haven't experienced the aftermath of this surgery.

Wishing you luck,  whatever you decide. xxxx
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Tempest

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Just adding - the ovaries continue to produce androgens due to the sparing of the stromal compartment well into old age, even if they are 'non viable' as regard to estrogen production. This is why, I feel, that women who retain ovaries have a greater sense of wellbeing than those who don't. xxxx
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Night_Owl

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Thanks to All for your comments and useful information - much appreciated and so helpful.

The ovaries would stay - 12 years post meno, they 'dissolved' a while back and I experienced a further decline overall.

The fear is how you're going to feel further down the line, a thousand questions - will it be worth it, can it worsen depression/anxiety.  So difficult as no way of knowing.  We're all so different.

Much pondering.  Just know for certain that whatever happens I can't ever take (any type) progesterone again.

Thanks again.

xxx
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