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Author Topic: Cyclogest-Anyone using?  (Read 3880 times)

Annieoj

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Cyclogest-Anyone using?
« on: June 06, 2018, 05:13:42 PM »

Hi there,

I wandered if anyone out there is using Cyclogest as the progesterone part of their HRT.

To cut a long story short, I have had difficulties getting Utrogestan prescribed and so the GP suggested Cyclogest (after seeking advice from menopause clinic).

He has prescribed to take (200mg) last two weeks of cycle, which I think means (based on a 28 day cycle) that I will be taking it 2 weeks on, 2 weeks off.

I just wandered if anyone else was using Cyclogest as HRT (although I don't think it is licensed for HRT) and if so what dosage do you take.

I also face the difficulty as from Feb this year I have been on Oestrogel and Norethisterone .35mg daily so haven't had a period.  I'm 48 and theoretically perimenopausal but hadn't had a period since July 17.   Do people just make a guess when don't know their cycle and just start?  The GP suggested wait 14 days after stopping norethisterone and then start?

Would be really interested from anyone either on Cyclogest or was in the past.  My GP is not a specialist so not sure where he got the recommended dosage from?

Many Thanks, annieoj
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Hurdity

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Re: Cyclogest-Anyone using?
« Reply #1 on: June 06, 2018, 08:00:44 PM »

Hi there Annieoj

 :welcomemm: (don't think I have already?)

Quite right Stellajane - you've remembered correctly!!!

Yes I've used Cyclogest in the past. When I first went onto HRT 11 years ago I tried evorel sequi patches for 3 months but the norethisterone did not agree with me so my wonderful female gynae specialist GP prescribed me Estradot patches with Cyclogest. This was before Utrogestan was available (at least not for HRT, if at all)  so there was no licensed progesterone for HRT.  I used this regime for 4 years quite happily (well sort of!).

She prescribed me 400 mg ie 2 x 200 mg pessaries/suppositories for 11 days per month (28 day cycle). I don't know where the dosage came from but it was/is used for fertility so I am guessing she made a calculation based on this. As they are waxy pessaries perhaps less is absorbed than with Utrogestan hence double the amount. However after about 3 years I stopped getting a withdrawal bleed so I imagine that was probably too much for a 28 days cycle with only 50 mcg oestrogen patch.

Without going into details I later changed to Utrogestan in autumn 2011 after a brief flirtation with a low dose conti regime (with Cyclogest every other day or maybe every third day) and then nothing for 3 months - and have been on it ever since.

Quite frankly I am surprised that a GP would prefer to prescribe a medication that is unlicensed for HRT over one that is licensed - as I said my GP only prescribed Cyclogest because Utro had not been invented. If your GP is not an expert gynae GP but prefers to use this rather than Utro then go with his suggestion. After all it is used vaginally ( or rectally) whereas vaginal use of utrogestan is also unlicensed for HRT in UK ( bizarrely - even though it gives better endometrial protection used like this). I suspect he got the dosage from the same dosage of utrogestan when used sequentially although they are not comparable as they are delivered and packaged differently (Utrogestan is micronised in suspension and Cyclogest is waxy pessary).

If you are peri-menopausal but haven't had a breakthrough bleed at all - then the norethisterone is successfully controlling your bleeding so you won't know whereabouts in your cycle you are. That being the case - yes, stop the norethsiterone for a fortnight - you may get a withdrawal bleed and then start the Utrogestan later, after a fortnight. You could actually take it every calendar month but it depends when you want to bleed  - I used to time mine accordingly!

Hope this helps and let us know how you get on!

Hurdity x
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Annieoj

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Re: Cyclogest-Anyone using?
« Reply #2 on: June 07, 2018, 01:41:01 PM »

Thankyou so much for the advice ( and the lovely welcome).  I had done some googling but the dosages I could find online were related to what it is licensed for, and not HRT, so wasn't sure. 

Your information is really really helpful....this HRT business is all so complicated! When I was prescribed the oestrogel, the first GP gave no prescribing instructions, so again a matter of googling and reading this forum to work it out :)

In respect of Cyclogest, the GP's dosage of 200mg for 14 days a cycle is slighlty lower dosage but might see how I get on with this (although a higher dose might be needed?).

Thanks again,

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Hurdity

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Re: Cyclogest-Anyone using?
« Reply #3 on: June 08, 2018, 07:20:00 AM »

Yes good idea to try 200 mg - I always felt 400 mg was too much but it did do the job effectively! The advantage of Cyclogest is that it can be used as a vaginal pessary or rectal suppository should you so wish - although with using a lower dose I imagine vaginal insertion would give more progesterone directly to the uterus where it is needed.

Good luck with it anyway!

Hurdity x
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