Hi Stephydavies. I have been on Femoston 1/10 and 2/10 and also Evorel Conti patches. First started off with Femoston 1/10 and must admit they took a while to even take the edge of anything to be honest!! I had a check up with the Dr and was still being woken up by the hot flushes and just general irritability this came with, so he increased the Femoston to 2/10. Well by jove!!! within the first weeks I felt brand new, like a Barbie doll!!! I was energetic, I didn't feel the need to scream and cry for absolutely no reason whatsoever, and I slept!! like a babe in arms. The joy didn't last as I have previous hypertension issues so after having a particularly high few months of BP readings the Dr said no more...... my god!!! It was like someone had removed my right arm. Within days I was back to angry, tired, hot sweaty mess me!!! after a few good BP readings and having a few hellish months the Dr Put me back on HRT but the conti patches. Again great, felt like I could accomplish anything but again it was short lived due to the adhesive on the patches not liking my derriere one jot!!!. So I am back on Femoston 1/10. Nearly at the end of my first week and I am still having flushes and they are still waking me up, but... I don't feel as irritable, I don't know if it's because I know when they are coming, the hot flushes I mean, so I can practice my breathing rather than becoming an anxious screaming crying banshee that I was originally. I have to visit my Dr again in three weeks time after my first month to see how I am doing. I am praying, oh lord I am praying that they will alleviate the symptoms, and I will carry on with the Femoston 1/10 so hang in there!!!