Sue, I just wanted to say that lots of us know and understand how you feel, and unless you've been there and done it, it's hard to understand how hormones can have such a huge impact on our lives, your friends just won't understand it at the moment if they are feeling fine. Concentrate on yourself and not how they seem to be treating you. I'm not an expert on thyroid either, but everything else you said in your first post relates to how I have been but for me it's been over a number of years, probably the anxiety was the first thing and I now think it was the start of peri but who really knows. There seems to be total lack of joined up thinking where I am in regards to how doctors treat all of the symptoms you've mentioned, I have had CBT, gastro investigations and gynae investigations all before I myself realised everthing was down to menopause - once the hot flushes started. No doctor or consultant mentioned it during any of these times. You have to take control of dealing with the issues and be persistent, I know it's very hard when you're exhausted and nobody really wants to hear about it. It sounds like you have done all that but things have got worse or changed so you need ongoing support. Last summer I could barely walk from the bus stop to home and was in tears and in bed as soon as I got in. I was in the GP's surgery at 5.55pm in tears asking to see the GP at the end of the day, really desperate. Really hideous for everyone! One thing really helped was high dose of vit D3 and menopace along with joint pain management. As you have said the thyroid is the first thing to sort out, get a GP that you can talk to and insist that you need help to be able to live your day to day life normally. It's not a lot to ask for and as you say it shouldn't be difficult. Good luck and let us know how you get on!