Just shows how we absorb so differently - different skin, fat content, site of application etc. I've never had a problem with patches and never really noticed them either running out or surges of aynthing when I put them on - maybe my levels do fluctuate but not to the extent that I think woah what's going on and looking for a pattern. As long as you find a way to give yourself as consistent dose as you can that works for you - then all good
![Smiley :)](https://www.menopausematters.co.uk/forum/Smileys/extended/smiley.gif)
If you feel it is running out before change time then maybe you need a higher dose - apply it at night and then you may not notice and by morning you should be OK?
Hurdity x