Hi there Defeated,
I am perimenopausal and have been using vagifem for about a year, both alone, and in addition to sequential hrt. I haven't had any side effects from using it, although I did think it was making me really sore and causing me to bleed. This was when I stopped the sequential hrt. I finally realised that my painful symptoms were because my oestrogen levels had dropped far to low, and I actually had to significantly increase my vagifem! I'm now back on Oestrogel and Utrogestan, and need far less of the vagifem. As the others have said, it's definitely worth persevering with. My GP said I could double the dose if things were really bad, 'topping and tailing' as she described it! One vagifem high up, and another lower in the vagina. Apparently there used to be two doses available, but the higher dose was discontinued. When only using one, I found the most benefit overall from inserting them lower rather than higher.
I really hope you see an improvement soon.
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