Well as you know from my post I react bad to SJW, I have arthritis in my back and dr has put me on amitriptyline, an antidepressant which used in low doses is meant to help nerve pain, I'm only 2 weeks in but I did fess up to her about my low mood and anxiety and she said start on 10mg and if I feel I need more go to 20mg, I'm tolerating the 10mg really well