Hi there, just looking for some advice. I am currently in peri menopause, previously tried Femoston 2/10 but suffered with migraines so GP changed to femseven sequi. I was very allergic to the patches. I use Vagifem every other day. I went to Nick Panay,s clinic and was prescribed Oestrogel 3 pumps a day and 12 days utrogestan 200mg orally, initially but was told if it does not suit could try vaginally. I was really pleased as this seems to be a good combination for many people. I used the Oestrogel for the first time yesterday and throughout the day developed itching all over, particularly my scalp and my anxiety went through the roof. I feel so disappointed. Today I only took 1 pump and have decided to increase slowly up to the 3 pumps, still a bit itchy but anxiety is only mild today. Has anyone else experienced this and it improved? Any advice? I am willing to stick it out but so worried this won't work for me. My main symptoms are VA, bladder problems long periods.