Waterdaggers, can relate to what you are saying as you're describing 'progesterone intolerance'. You may have seen other threads discussing this. As you may or may not know, it's the main reason women give up HRT. Of the women who take HRT, roughly 20% are 'progesterone intolerant' and within that group, 10% are 'severely progesterone intolerant', which also means being 'allergic' to one's own progesterone too. I am in the latter group, I know this as I also had hideous PMT, probably Premenstrual Dysphoric Disorder.
I agree with your fear of the finality of hysterectomy (I was offered this too and still pondering, years later) however that can bring with it other problems, eg bladder issues. Also the body can still produce small amounts of progesterone in the adrenals so although you wouldn't be taking additional progesterone, there is the possibility of still feeling some prog effects from your own production.
It sounds as if you need a lot more time to mull this over.
The Utrogestan 200mg is very heavy duty. Do you take it v-route?
In the meantime:
* wondering if it would be possible for you to take a long cycle regime, it still means taking Utro but less often, ie. every 6/7 weeks. I'm sure Hurdity will be along at some stage to explain further, as this is her regime.
* I believe there are members who take Utro for just 7 days per month with regular scans. As you know, it's all a balancing act and depends where you are in meno, it's still early days for you.
[By way of information, in my case and with years of trips to the meno clinic and discussion about my severe prog intolerance, the best (but not ideal regime) is low dose estrogen Estraderm 25 and 100mg Utrogestan x 12 every 6/7 weeks. Which means I have 6 or 7 weeks of 'estrogen holiday'. I dread taking the Utro with every fibre of my being but I know it's an evil necessity! I am further along the meno journey - my periods stopped at 44 and it's now 9 years on. In the early days I could never take high doses of estrogen as I couldn't take the necessary level of progesterone. I tried them all eg. Crinone, Cyclogest and wouldn't consider the Mirena - all the progesterones made me feel beyond hideous.]
* Just a suggestion - Maybe a 37.5 Estradot estrogen patch and lower dose 100mg Utrogestan, v-route x 12 nights, every 6 weeks - with 6 monthly endo scans.
* No HRT at all - up your supplements, eg. Magnesium, Vit D, Calcium Carbonate.
Unfortunately there is no escaping the dreaded progesterone.
I hope you find a way forward.
