Hi Prudence!
If it's any help regarding adverse reactions, I must be the worst case scenario and I have just started using Estrogel! I have multiple drug allergies that cause anaphylaxis, and my surgeon was very reluctant to start me on anything and I went 1 full year following my TAH/BSO with nothing.
I found a lady Consultant at my local Menopause Clinic who felt confident enough to help me. I was very, very anxious about it! We chose transdermal HRT as this doesn't go via the liver, and therefore the risk of a catastrophic reaction is much, much less. And guess what? Nothing bad has happened and I am probably the most allergic person you could wish to meet! I was actually under the specialist anaphylaxis clinic here for over 3 years for testing and monitoring, just so that you get the idea! You can start on a very small dose if you are nervous, just to 'test' and build up your confidence, and then move to the therapeutic dose that is right for you after a couple of days if all is well (which I'm confident it will be)!
As I understand it, it is not usual to experience significant weight gain on HRT. A bit of fluid retention is usual, but usually settles down too as your body adjusts. I'm just over a month on the Estrogel, and have gained just 3 pounds which actually fluctuates throughout the day (I.e., I'm no heavier than before HRT in the morning, but get a little puffier as the day moves on). Your sense of well-being should improve, so you will hopefully be more active too - so that will be a bonus to maintaining a good weight.
I'm sure some of the more experienced ladies will be along soon to offer more advice, but I just really wanted to respond to the allergy issue for you.😊