Interesting your mention of your dear gran stellajane. Both my grans live to 94, never took HRT, never indulged in organised exercise - housework without all the mod cons was enough exercise and my Nan did a lot of gardening too. Natural foods cooked from scratch, no processed foods, walked everywhere, plenty of fresh air. Nan gave up smoking at the age of 60 and lived to 94 having a small stroke 3 days before she died. Gran was a bit of a recluse during her last 2 decades, hardly went out and did a lot of sitting so was probably low in vitamin D. She wasn't a pleasant character but rarely went to the doctors.
Nan especially didn't suffer foolishness, grafted hard all her life, not an ounce of self pity and no illness other than colds.
In my opinion the modern age with its stress, dietary choices, sedentary lifestyles and its obsession with 'healthy living' is not good for us. We are all too self focussed and worried instead of just living.
One of the only upsides I can see is that children do not die of so many infectious illnesses these days but they get other things instead - childhood obesity and type 2 diabetes for example.