Having an aunt, who had breast cancer, is not a bar to taking HRT, as long as you do not have 2 or more close relatives who have had breast cancer. Mothers and sisters are close relatives. In fact my sister died from oestrogen sensitive breast cancer, but as I have no other close relatives who have had breast cancer, she is considered 'a blip' in my family history, in the words of a breast cancer consultant. Obviously, I was worried and avoided HRT for many years, but quality of life outweighed the risks to me.