This is something that is very tempting to try, and I had considered it, but believe it is best to do if you are on gel. If you are going to experiment a bit I think it would be good to keep a mood journal so you can see if there is some sort of pattern and you can anticipate when you may need some extra. My gynae did speak to me about this as well and often starting out for women in perimenopause will prescribe 1 mg of oral estrogen only for 7-10 days before cycle starts and no progesterone. So many different things to consider, good luck and let us know if you decide to experiment and what results you get....Good Luck.