I take Yaz Chi chi and have done for 5 years now. My doctor recommended it when I was having an erratic time in peri-menopause and it has been wonderful. No depression, no mood swings, lots of energy and great skin. The progesterone in YAZ (drospirenone) is closest to bio-identical and was well tolerated.
Negatives are 10lb weight gain (though maybe I eat and drink too much!) and complete loss of sexual response. As I was ending a dysfunctional relationship at the time and have remained single since, that has not been a huge problem. Overall, I have felt fabulous.
Now that I am 57 my doctor has suggested I transfer from YAZ to HRT. In theory that sounds like a good idea but in practice I have had a terrible time transitioning (tried for 3 months with all sorts of terrible physical and emotional side effects) and have recommenced taking YAZ.
What I would like to do now is make a plan to reduce YAZ and commence bio-identical hormones at the same time so the consequences are not as dire as when I went cold turkey. Not sure how to manage this as what is Ethinyl estradiol 20mcg equivalent in estrogen?
That is my troubling issue, in relation to your enquiry: I have found YAZ to be excellent and effortless. The only reason I am now reluctantly stop taking it is on doctor's advice and because I (also reluctantly) think I should make an effort to have another sexual relationship before my life ends - and I will need some kind of sexual desire and response to achieve this!