I'm 41 peri although Estrogen still low normal range progesterone low. So I've been put on 100mcg patch as depression one of prominent problems. Been on it 2.5 weeks and since starting feel like I am on the verge of tears all day and anxiety worse. I think it's too high. And from what I've read on here very few are on such a high dose. And I read three pumps Estrogel equivalent 50mcg patch which means I'm taking the equivalent of six pumps wtf! So I've got some 1mg sachets of sandrena think I might switch. Thoughts? I'm still having a one day light period each month but have been months without one. Dr currie suggested sandrena then utrogestan then this other endo put me on the 100mcg!