I'm in a bit of a mess and could do with some advice. I've always had problems with my periods, started perimenopause about 4years ago, started hrt elleste duet when symptoms were awful mostly night sweats, moods, headache and flushes all the time, so was on low dose then after a while upped the does that was fine. Was on these about 2 years 2 and a half, came off, no more bleeding afte about 8 months couldnt cope with the night sweats and flushes anymore so went onto kliovance continuous low dose, that was fine for nearly a year i think maybe not quite as long, except for spotting which i think was a side effect but have to have a smear and internal to check. As the night sweats are back and driving me nuts plus headaches and awful temper tantrums (dont know how else to describe them and a lot of crying) I talked to dr and he suggested premique lose dose to se how that goes, says theres a higher risk of breast cancer being over 52 and best to start on a low dose. I dont know much baout these and am wondering if swopping alose dose for a low dose will make a difference, kliovance is 1mg estradiol & 0.5 mgs norethisterone daily. and premique is 0.3mg conjugated estrogen & 1.5mg MPA daily, i dont understand the difference, can anyone help or point me in the direction of help, thankyou x