There is something you can buy without a prescription called phenazopyridine (sp?), that is the chemical name, that can give some relief even without a UTI as it sort of helps numb the area after you urinate. It turns your urine orange. You can only take it for a few days at a time as it can be hard on your liver, but it does take the edge off the discomfort for really bad days. I took Vagifem for a long time before it helped much but I was way gone into VA and already needed systemic HRT by the time I figured out the problem. The vagifem wasn't dissolving so I wasn't getting much benefit. I basically had a vagina that had no internal liquid. If that is your issue also, you might try some vitamin E suppositories or some naturally oily substance or lubricant with the vagifem to give it some liquid to dissolve with. The estrogen creams can help if you are that dry, but I couldn't tolerate them....I must be allergic to something in them and they made me burn worse!