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Author Topic: New member  (Read 2980 times)

Thirtyeightnotout

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New member
« on: August 16, 2013, 06:37:45 PM »

Hi all,

I had a TAH & bi-oophrectomy last Sept at the tender age of 37 due to horrendous periods, PCOS, etc and have had a rollercoaster ride with HRT ever since.  Started with implant which failed then had Climaval 4mg daily plus Evorel 100 patches plus Metformin which increased my oestrogen to 1000. 
However, last month I started getting hot flushes so have had blood tests to see what is happening to my levels.  I don't miss the debilitating periods but the hot flushes and bloated stomach are getting me down. :(
Any advice would be greatly received.
Thanks,
Donna
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CLKD

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  • Posts: 75144
  • changes can be scary, even when we want them
Re: New member
« Reply #1 on: August 16, 2013, 09:36:53 PM »

 :welcomemm:  have a read of the menus left of screen and find our 'funny '  room - ask away!  Nothing is taboo here ..........
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Dyan

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  • Posts: 4216
Re: New member
« Reply #2 on: August 16, 2013, 09:57:05 PM »

 :welcomemm: thirtyeightnotout.

You will get lots of support on here.
It has been a lifesaver for me and a great laugh too!
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Joyce

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Re: New member
« Reply #3 on: August 17, 2013, 10:18:03 AM »

I had total hysterectomy in my mid 30s. My GP put me on HRT tablets, Premarin, initially. But developed a lactose intolerance after being pumped full of antibiotics when I had pneumonia a few years later. So switched to gel, now patches.
Sounds like you need to change to something else.
Have you a meno clinic near you at all? Ask your GP. Mind you I had to pester a few GPs before one got me referred to meno clinic at hospital near me.
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Thirtyeightnotout

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Re: New member
« Reply #4 on: August 18, 2013, 06:24:05 PM »

Hi cubagirl,
Thanks for the tip.  I'll ask my GP.  :thankyou:
I feel like I'm in limbo & all the other friends & colleagues that had a hysterectomy at my age have still got their ovaries so they're not suffering so much  :hotflash:
This is such a good forum & gives me hope that I'll get the right balance soon.
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Hurdity

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Re: New member
« Reply #5 on: August 19, 2013, 10:21:11 PM »

Hi 38notout
 :welcomemm: from me too.

Just to say that sometimes in cases like yours if you have too much oestrogen you get what's known as supraphysiological oestrogen levels and then something occurs called Tachyphylaxis when the oestrogen ceases to have an effect.

There is some information on it here on Prof Studd;s site:
http://www.studd.co.uk/implants.php

Are your levels in p mol/l or pg/mol? His are in pmol/l for direct comparison if yours are too.

The problem is can be that in natural menstruation the levels cycle between very high and much much lower whereas when oestrogen is replaced following hysterectomy the levels are consistently very high, which doesn't happen in nature. I don't know what the answer is but sounds like you are under specialist care so hopefully having good advice and treatment?

From what I have read there is a "sweet spot" which gives you just the right amount to keep the flushes etc at bay and to make you feel good too, and not too high to have the reverse effect - the knack is trying to find it!

Has anyone suggested testing for testosterone as this may be low too following your operation?

There is some information on this site here

http://www.menopausematters.co.uk/testosterone.php

and here:
http://www.menopausematters.co.uk/aftermeno.php (scroll down)


Role of testosterone after hysterectomy

If the ovaries are removed at the time of hysterectomy, as well as the estrogen level falling, there is also a 50% decrease in testosterone production. Some doctors recommend testosterone replacement along with estrogen replacement; testosterone helping energy levels, mood and libido. However testosterone replacement does not seem to be required by all and the ideal route and dose of testosterone for women is still being researched. It is therefore not routinely recommended following removal of the ovaries but can be considered for some women who do not fully benefit from estrogen replacement alone.



as well as on Prof Studd's site I linked to above.


Hope this helps

Hurdity x
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Thirtyeightnotout

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Re: New member
« Reply #6 on: August 22, 2013, 06:08:34 PM »

Hi Hurdity,

Thanks for that info - very useful indeed! :)
My previous blood test results were in pmol/l.  I've just got my most recent test result back and my oestrogen level is up to an all-time high of 1851 pmol/l!  This is surprising as I thought it would be lower due to my frequent sweats & mood swings  :o
Waiting to see what the specialist says next but it sounds like I may well be suffering from Tachyphylaxis which would explain the sudden sweats which I've only had for the last month.
I really appreciate the help & makes me feel less bewildered by it all  :thankyou:

Donna x
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